The forgotten fat-burning and muscle-building benefits of carnitine

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An exciting new study published in the prestigious Journal of Nutrition confirms that carnitine has powerful muscle-building and fat-burning effects. Researchers from the University of Naples found that just one month of treatment with carnitine reduced the storage of fat while also increasing body protein percentage in rats. This confirms the results of previous trials showing that carnitine increases the use of fat for energy, making it easier for you to maintain a lean and defined appearance.

Human research also shows that supplementation with L-Carnitine can significantly increase fatty acid oxidation in healthy adults. This study conducted at the University of Rostock (Germany) has been published in the journal Metabolism.

L-Carnitine occurs naturally in the human body and is frequently referred to as the "energy nutrient". This is because its primary physiological role in the human body relates to the generation of energy from fat. L-Carnitine carries long chain fatty acids into the mitochondria where they are oxidized for energy. Among physically active people who supplement with this nutrient to help with post-exercise recovery, L-Carnitine has been popular for many years. Extensive clinical research indicates that L-Carnitine promotes cardiovascular health, and studies also suggest that L-Carnitine may be useful as part of a weight management program.

The present clinical study was conducted under guidance of Prof. Klaus D. Wutzke. It was set up to verify breakthrough results that conclusively show oral L-Carnitine supplementation boosts fatty acid metabolism in healthy adults. By using a different approach, namely a combined 15N-, 13C-tracer technique, the effects of oral L-Carnitine supplementation on fatty acid oxidation in slightly overweight adults were investigated.

After oral administration of the labelled fatty acids and the amino acid glycine, 15N- and 13C-enrichment in breath was measured by isotope ratio mass spectrom etry. The researchers observed a significant increase in 13CO2 exhalation after L-Carnitine supplementation, which indicates an increase in fatty acid oxidation.

Iossa S, Mollica MP, Lionetti L, Crescenzo R, Botta M, Barletta A, Liverini, G. (2002). Acetyl-L-carnitine supplementation differently influences nutrient partitioning, serum leptin concentration and skeletal muscle mitochondrial respiration in young and old rats. Journal of Nutrition, 132, 636-642
Wutzke KD, Lorenz H. (2004). The effect of l-carnitine on fat oxidation, protein turnover, and body composition in slightly overweight subjects. Metabolism, 53, 1002-1006

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3.26 Copyright (C) 2008 / Copyright (C) 2007 Alain Georgette / Copyright (C) 2006 Frantisek Hliva. All rights reserved."